By National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Board on Life Sciences, Human Embryonic Stem Cell Research Advisory Committee
In 2005, the nationwide Academies published the record guidance for Human Embryonic Stem phone examine, which provided a standard set of moral criteria for a box that, as a result absence of entire federal investment, used to be missing nationwide criteria for research.
In order to maintain the information modern, given the speedy velocity of clinical advancements within the box of stem cellphone learn, the Human Embryonic Stem telephone learn Advisory Committee used to be verified in 2006 with aid from The Ellison clinical starting place, The Greenwall beginning, and the Howard Hughes clinical Institute.
As it did in 2007, the Committee pointed out concerns that warranted revision, and this publication addresses these concerns in a moment set of amendments. most significantly, this booklet addresses new clinical advancements in reprogramming of somatic cells to pluripotency via including a brand new part and revising different correct sections of the Guidelines.
Read Online or Download 2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research PDF
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Extra info for 2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research
Gastrulation—The procedure by which an animal embryo at an early stage of development produces the three primary germ layers: ectoderm, mesoderm, and endoderm. Gene—A functional unit of heredity that is a segment of DNA located in a specific site on a chromosome. A gene usually directs the formation of an enzyme or other protein. Gene targeting—A procedure used to produce a mutation in a specific gene. Genital ridge—Anatomic site in the early fetus where primordial germ cells are formed. Genome—The complete genetic material of an organism.
In the case of lines imported from another institution, documentation that these criteria were met at the time of derivation will suffice. 1. 3 Each institution should maintain a registry of its investigators who are conducting hES cell research and ensure that all registered users are kept up to date with changes in guidelines and regulations regarding the use of hES cells. 4 All protocols involving the combination of hES cells with nonhuman embryos, fetuses, or adult animals must be submitted to the local IACUC for review of animal welfare issues and to the ESCRO committee for consideration of the consequences of the human contributions to the resulting chimeras.
Ingram Professor in the Department of Cell Biology at Vanderbilt University Medical Center. Dr. Hogan earned her PhD in biochemistry at the University of Cambridge. She was then a postdoctoral fellow in the Department of Biology at the Massachusetts Institute of Technology. Before moving to the United States in 1988, Dr. Hogan was head of the Molecular Embryology Laboratory at the National Institute for Medical Research in London. Her research focuses on the genetic control of embryonic development and morphogenesis, using the mouse as a model system.
2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research by National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Board on Life Sciences, Human Embryonic Stem Cell Research Advisory Committee