By Atta-Ur-Rahman
ISBN-10: 0444510044
ISBN-13: 9780444510044
Quantity 26 of "Studies in normal Product Chemistry" offers the chemistry of a big variety of interesting ordinary items. all the chapters mirror the significance of the organic task of nature's molecules - task which keeps to motivate the evolution of recent medicinal drugs opposed to sickness. issues coated comprise: the triterpenoid saponins from the Caryophyllaceae kin; advancements within the overall synthesis of bioactive marine fatty acids; and the chemistry and organic job of secologanin, lignans, saffron and the bark of Fraxunus ornus. more than a few traditional compounds that are utilised within the evaluate of environmental matters also are mentioned, as are the pharmacological actions and functions of crucial oils, plant progress regulators and phytotoxins. The chemistry and bioactivity of secondary metabolites is reviewed during this quantity, including the constitution, chemistry and organic task of resveratrol oligomers. fresh advancements within the chemical behaviour, toxicology and chemical ecology of compounds present in bracken fern are reviewed. The prevalence, constitution and bioactivity of 1,7-diarylheptanoids is roofed, including the buildings and organic actions of normal pesticides. capability anti-parasitic substance from ordinary resources is gifted right here, as is the chemistry and bioactivity of nitric oxide (NO) in plant and animal cells. The function of O-aminophenol-type tryptophan metabolites in dwelling organisms can be mentioned.
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Additional resources for Bioactive Natural Products (Part G), Volume 26
Sample text
Popularly known as fuller's herb or soapwort, is native to Europe and western to central Asia, and is presently cultivated in different parts of the world for its medicinal properties. This plant was well known for its detergent property and was used as soap in ancient times. In folk medicine it is used for various skin diseases, rheumatic disorders and as an expectorant for bronchitis [35]. In Europe, different parts of the plant, viz. the roots, rhizomes and shoots are used for the preparation of herbal medicines [36].
Oldhamiana [78], which has been used as a substitute for the wellknown traditional Chinese medicinal herb Sterllaria dichotoma var. lanceolata in the treatment of fever, consumptive disease, and infantile malnutrition. The most polar saponin was a bisdesmoside and its structure was established as shown in Fig. (26). The other two saponins were monodesmosides derived from C-28 methyl esters of quillaic acid and gypsogenin and having identical sugar moieties at C-3. Rha HO' HOCH3 /0> HOHO' X > ^ HO "OH Glc Fig.
Rha HO' HOCH3 /0> HOHO' X > ^ HO "OH Glc Fig. (26). Saponin from Gypsophila oldhamiana. Very recently. Delay et al. reported the isolation and characterization of two highly hemolytic saponins from the commercial Merck saponin (roots of G. paniculatd) (Fig. 27) [24]. The two compounds (SAPO 50 and SAPO 30), which possessed 25% and 1% of the total hemolytic activity of the crude Merck saponin extract, were purified by dialysis, reverse phase C-18 column chromatography, and HPLC with monitoring of hemolytic activity.
Bioactive Natural Products (Part G), Volume 26 by Atta-Ur-Rahman
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