This case-based studying publication information 25 hard instances in cardiovascular drugs masking all subspecialty components of cardiology. it really is designed for use through trainees yet every one case is supported by means of the statement of a popular specialist within the box, permitting readers to enhance their very own administration of those patients.
As the reader works via every one case there are 'Clinical Tips', 'Learning Points' and 'Landmark Trial Summaries' to reinforce the training method in addition to the 'Expert Commentary', supplying an inside of tune on how the specialists process all these demanding instances.
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Additional resources for Challenging Concepts in Cardiovascular Medicine: Cases with Expert Commentary
The superior tolerability of clopidogrel when compared to ticlopidine was ﬁrst established by the CLASSICS trial . Subsequently, due to its adverse side effect proﬁle and slower onset of action, ticlopidine use fell dramatically and was replaced by the much safer, equally effective and, when a loading dose was given, signiﬁcantly faster-acting clopidogrel. 1) [6-13]. 002 *Clopidogrel arm; †Aspirin ± placebo arm; ER: event rate; RRR: relative risk reduction; CVA: cerebrovascular accident; PAD: peripheral arterial disease; ASA: aspirin.
New Engl J Med 2001; 344: 1117–1124. 26 Daemen J, Kuck KH, Macaya C, et al. Multivessel coronary revascularization in patients with and without diabetes mellitus. 3-year follow-up of the ARTS II trial. J Am Coll Cardiol 2008; 52: 1957–1967. 27 Serruys PW, Morice M-C, Kappetein AP, et al. for the SYNTAX Investigators. Percutaneous coronary intervention vs coronary artery bypass grafting for severe coronary artery disease. N Engl J Med 2009; 360: 961–972. 28 Sianos G, Morel M-A, Kappetein AP, et al.
Some may argue, however, that an observational approach reflects a more ‘real-world’ viewpoint of clinical practice and should be considered a supportive adjunct to RCT data. 9 10 Challenging concepts in cardiovascular medicine For instance, Hannan et al. looked at 37,212 individuals with MVD undergoing CABG against 22,102 MVD patients receiving PCI (with stenting) during a 3-year period between 1 January 1997 and 31 December 2000 in New York State . The authors reported a significantly improved ‘risk-adjusted’ survival rate for those having had CABG in all of the anatomical subgroups studied along with, as expected, a much higher repeated revascularization rate for patients having had PCI as their index procedure.
Challenging Concepts in Cardiovascular Medicine: Cases with Expert Commentary